Progestogen hypersensitivity: case report

Autores/as

  • Marta Evangelho Machado University of Cincinnati
  • Jonathan Abram Bernstein Souza Marques Techno-Educational Foundation, Department of Pediatrics, Division of Pediatric Allergy/Immunopathology Section

DOI:

https://doi.org/10.5327/JBG-0368-1416-202213201

Palabras clave:

progestins, hypersensitivity, progesterone, pruritus

Resumen

Progestogen hypersensitivity is characterized by heterogeneous skin eruptions that cyclically aggravate during the luteal phase of the menstrual cycle, corresponding to a rise in progesterone levels. The clinical presentation is highly variable, with urticarial, angioedema, and eczematous lesions being prominent. Both endogenous progesterone and exogenous progestogens may represent an initial trigger. We report the case of a 42-year old woman who was unresponsive to all treatments, including progestin desensitization, that ultimately required bilateral oophorectomy to control her symptoms.

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Publicado

2022-08-12

Cómo citar

Machado, M. E. ., & Bernstein, J. A. . (2022). Progestogen hypersensitivity: case report. Jornal Brasileiro De Ginecologia, 132. https://doi.org/10.5327/JBG-0368-1416-202213201

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